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Registration date period
Results ordered by trial registration date, descending.
  1. Study of ACE-083 in Patients With Facioscapulohumeral Muscular Dystrophy (FSHD)

    Registration date:
    Status:
    Ongoing
    Recruitment status:
    Recruiting
    Source name:
    ClinicalTrials.gov

    Study A083-02 is a multicenter, Phase 2 study to evaluate the safety, tolerability, pharmacodynamics (PD), efficacy, and pharmacokinetics (PK) of ACE 083 in patients with FSHD to be...

    Conditions:
    • Facioscapulohumeral muscular dystrophy
    Interventions:
    • ACE-083
    • ACE-083 or placebo
  2. Effects of NMES on Muscle Function of Patients With FSHD: a Double-blind Randomized Controled Clinical Trial

    Registration date:
    Status:
    Ongoing
    Recruitment status:
    Recruiting
    Source name:
    ClinicalTrials.gov

    Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant disease characterized by progressive weakness and atrophy of specific skeletal muscles. One of the major problems of...

    Conditions:
    • Primary Disease Facioscapulohumeral Dystrophy (FSHD)
    Interventions:
    • Current flow between sensory and motor threshold
    • Current intensity upper of motor threshold by Kneehab XP technology
  3. Study to Evaluate the Long-Term Safety, Tolerability, and Biological Activity of ATYR1940 in Patients With Limb Girdle and Facioscapulohumeral Muscular Dystrophy

    Registration date:
    Status:
    Complete
    Recruitment status:
    Not recruiting
    Source name:
    ClinicalTrials.gov

    ATYR1940-C-006 is a multi-national, multicenter study being conducted at centers in the United States (US) and Europe who participated in the Study ATYR1940-C-003 (Stage 1 only) or ...

    Conditions:
    • Facioscapulohumeral muscular dystrophy
    • Limb-girdle muscular dystrophy
    Interventions:
    • ATYR1940
  4. An Study to Evaluate the Long-Term Safety, Tolerability, and Biological Activity of ATYR1940 in Patients with Limb Girdle and Fascioscapulohumeral Muscular Dystrophy

    Registration date:
    Status:
    Terminated
    Recruitment status:
    Not recruiting
    Source name:
    EU Clinical Trials Register

    To evaluate the safety, tolerability, and immunogenicity of long-term treatment with intravenous (IV) ATYR1940 in patients with limb girdle muscular dystrophy 2B (LGMD2B) or fascioscapulohumeral...

    Conditions:
    • Limb Girdle Muscular Dystrophy and Facioscapulohumeral Muscular Dystrophy
    Interventions:
    • ATYR1940
  5. Rasch-analysis of Clinical Severity in FSHD

    Registration date:
    Status:
    Ongoing
    Recruitment status:
    Not recruiting
    Source name:
    ClinicalTrials.gov

    The purpose of this study is to make a standardized and scalable Rasch-built clinical severity scale to help in finding genetic and environmental modifiers of disease in ...

    Conditions:
    • Facioscapulohumeral muscular dystrophy
    Interventions:

    Unknown

  6. Facioscapulohumeral Dystrophy in Children

    Registration date:
    Status:
    Ongoing
    Recruitment status:
    Recruiting
    Source name:
    ClinicalTrials.gov

    This study will focus on the symptoms, natural history and clinical impact of facioscapulohumeral muscular dystrophy (FSHD) in children. Symptoms of classical FSHD start in adulthood....

    Conditions:
    • Neurological Observations
    • Facioscapulohumeral muscular dystrophy
    • Pediatric Disorder
    Interventions:

    Unknown

  7. The Safety and Biological Activity of ATYR1940 in Patients With Limb Girdle or Facioscapulohumeral Muscular Dystrophies

    Registration date:
    Status:
    Complete
    Recruitment status:
    Not recruiting
    Source name:
    ClinicalTrials.gov

    The purpose of this study is to assess the safety and biological activity of ATYR1940 in patients with Limb Girdle (LGMD2B) or Facioscapulohumeral Muscular Dystrophy (FSHD).

    Conditions:
    • Limb-Girdle Muscular Dystrophies
    • Facioscapulohumeral muscular dystrophy
    Interventions:
    • ATYR1940
    • Placebo
  8. Muscle Inflammation and Fat Infiltration in Patients Affected by FSHD

    Registration date:
    Status:
    Ongoing
    Recruitment status:
    Recruiting
    Source name:
    ClinicalTrials.gov

    Facioscapulohumeral muscular dystrophy (FSHD) is the second most common muscular dystrophy with approximately 500 patients in Denmark. It is characterized by weakness and wasting of the...

    Conditions:
    • Facioscapulohumeral Muscular Dystrophy 1a
    Interventions:
    • No intervention; observational
  9. A Study to Evaluate the Safety, Tolerability, Immunogenicity, and Biological Activity of ATYR1940 in Patients with Limb Girdle and Facioscapulohumeral Muscular Dystrophies

    Registration date:
    Status:
    Complete
    Recruitment status:
    Not recruiting
    Source name:
    EU Clinical Trials Register

    To evaluate the safety, tolerability, and immunogenicity of the weekly and twice weekly intravenous (IV) administration of ATYR1940, at doses of 0.3, 1.0, and 3.0 mg/kg, to patiens with...

    Conditions:
    • Limb Girdle Muscular Dystrophy and Facioscapulohumeral Muscular Dystrophy
    Interventions:
    • ATYR1940