This study is to determine the efficacy (how well the drug works), safety, and any side effects of olanzapine compared to placebo in the treatment of schizophrenia in adolescents. Both the potential benefits and side effects of olanzapine will be evaluated throughout this trial.
- The safety of olanzapine in adolescents with schizophrenia or bipolar I disorder: a pooled analysis of 4 clinical trials.
- Olanzapine versus placebo in adolescents with schizophrenia: a 6-week, randomized, double-blind, placebo-controlled trial.
The methodological rigour of this trial was scored in a systematic review, where it was scored as being at "unclear" for "sequence generation", "unclear" for "allocation concealment", "low risk" of bias for "blinding (performance)", "low risk" of bias for "blinding (detection)", "low risk" of bias for "attrition", "low risk" of bias for "reporting", and "low risk" of bias for "other biases". Read more about what this means.